The Committee on the Clinical Application of Cardiac Biomarkers (C-CB) of the IFCC represents international groups from laboratory medicine, cardiology and emergency medicine involved with providing global educational guidance pertaining to the analytical and clinical applications of cardiac biomarkers.

Although the recently published "2020 European Society of Cardiology (ESC) guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation" are extremely useful, our presentations will delineate specific concerns regarding the guidance for the use of high-sensitivity cardiac troponin. The concerns we will address are relevant to the international laboratory medicine community.