This webinar will give an overview of how high sensitivity troponins may be used for rule-out and rule-in of non-ST elevation myocardial infarction, including data on safety and efficiency. The laboratories role as facilitator in implementation of current recommendations for measuring troponins in the emergency room will be discussed. The webinar will also describe long-term risk in the heterogenic group of patients who do not have acute myocardial infarction and how cardiac markers may help identify individuals who could benefit from a closer follow-up.